My laboratory is focused on the fundamental question– “How do synapses enable neuronal circuits to transmit a wide diversity of information?” Outcomes from our work will define the molecular principles that govern how synaptic properties drive neuronal circuit output which underpins organism behavior. These molecular principles uncovered may reveal the underlying causes of neuronal circuit dysregulation which results in neuropsychiatric or neurodegenerative diseases and have the potential to give rise to new therapeutic treatments.