Charles Brenner , PhD
Aging Related Research:
I discovered nicotinamide riboside (NR) as an unanticipated vitamin precursor of NAD and showed that NR extends lifespan in yeast by virtue of increasing NAD metabolism and Sir2 activity. I have further investigated the metabolic consequences of calorie restriction and am engaged in metabolism research in several conditions related to aging.
Keywords: Nicotinamide riboside, NAD, metabolomics, calorie restriction