Al Klingelhutz

Al Klingelhutz

Associate Professor
Microbiology
Phone: 
319-335-7788

One of my primary interests is in how epithelial cells become immortal and subsequently malignant after infection with human papillomavirus (HPV). We are also studying how telomere loss and other factors are involved in induction of cellular senescence and aging. More recent studies have focused on the role of adipocytes in the development of diabetes and other metabolic disorders. Specific areas of research are:

  • Determining how bacterial toxins and environmental pollutants disrupt metabolism through their effects on adipocyte differentiation and function
  • Developing strategies to inhibit the growth of HPV transformed cells
  • Defining the role of telomere loss in aging and cancer
  • Characterizing how cellular genes are regulated by HPV E6 and E7 during the process of infection and transformation
Categories: 
Basic Sciences